Following the publication of the Environmental Noise Guidelines for the European Region (ENG), a lot of debate has focused on the Guideline Recommendations, in particular the specific guideline levels and the strength of the recommendations. Nevertheless it is widely acknowledged that a sizeable proportion of the population is currently exposed to noise levels above the WHO recommendations, and it is important for policy and decision makers to be able to quantify the associated burden of disease as accurately as possible. From this perspective, the systematic reviews of the scientific evidence commissioned by the WHO are an equally important aspect of the ENG.In the UK the current recommended methodology for valuing health impacts associated with environmental noise is outlined in two documents published by the Department for Environment Food and Rural Affairs (Defra) and the Interdepartmental Group on Costs and Benefits Noise Subject Group (IGCBN). [1,2] This paper will look into the studies that informed the exposure response relationships recommended by these two documents. A comparison is then made with the more recent studies that informed the ENG, followed by a discussion of which aspects of a study would make it more applicable to a local population.